KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT1A
All Species:
44.24
Human Site:
Y225
Identified Species:
69.52
UniProt:
P49585
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49585
NP_005008.2
367
41731
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Chimpanzee
Pan troglodytes
XP_001143741
320
37092
Q196
T
R
I
C
R
D
Y
Q
V
F
A
T
V
N
T
Rhesus Macaque
Macaca mulatta
XP_001090055
338
38695
D214
T
R
I
V
R
D
Y
D
V
Y
A
R
R
N
L
Dog
Lupus familis
XP_535776
367
41764
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Cat
Felis silvestris
Mouse
Mus musculus
P49586
367
41648
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Rat
Rattus norvegicus
P19836
367
41662
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517894
294
33692
L169
I
N
E
K
K
Y
H
L
Q
E
R
V
D
K
V
Chicken
Gallus gallus
XP_422725
367
42078
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Frog
Xenopus laevis
NP_001089299
367
41920
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Zebra Danio
Brachydanio rerio
NP_001018571
359
41135
Y222
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647621
526
58183
Y354
R
R
N
L
A
R
G
Y
S
A
K
E
L
N
V
Honey Bee
Apis mellifera
XP_395764
403
46370
Y262
R
R
N
L
A
R
G
Y
S
A
K
E
L
N
V
Nematode Worm
Caenorhab. elegans
P49583
362
41751
Y229
R
R
N
L
Q
R
G
Y
S
P
K
E
L
N
V
Sea Urchin
Strong. purpuratus
XP_001180754
425
48260
Y241
R
R
N
L
S
R
G
Y
S
A
R
D
L
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13259
424
49388
A252
M
R
N
F
A
R
G
A
T
R
Q
E
L
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
60.7
96.4
N.A.
96.1
96.4
N.A.
77.3
89
86.3
76.2
N.A.
36.1
46.4
37.8
45.4
Protein Similarity:
100
69.2
71.6
98
N.A.
97.5
97.2
N.A.
78.1
95
91.2
84.1
N.A.
46
62
52.3
60
P-Site Identity:
100
13.3
13.3
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
86.6
86.6
86.6
73.3
P-Site Similarity:
100
26.6
33.3
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
93.3
93.3
93.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
0
7
0
67
14
0
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
14
0
7
0
0
0
7
7
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
0
7
0
74
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
80
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
7
7
0
0
0
0
0
67
0
0
7
0
% K
% Leu:
0
0
0
74
0
0
0
7
0
0
0
0
80
0
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
80
0
0
0
0
0
0
0
0
0
0
94
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
54
0
0
7
7
0
7
0
0
0
0
% Q
% Arg:
74
94
0
0
14
80
0
0
0
7
14
7
7
0
0
% R
% Ser:
0
0
0
0
7
0
0
0
27
0
0
0
0
0
0
% S
% Thr:
14
0
0
0
0
0
0
0
54
0
0
7
0
0
7
% T
% Val:
0
0
0
7
0
0
0
0
14
0
0
7
7
0
87
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
14
74
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _